abstract：:Hemangioendothelioma of the liver is a rare tumor. A case is reported of a middle-aged woman who presented with hepatomegaly and ascites, and who has been followed for over 12 years. The clinical features, pathological, radiographic, portal hemodynamic, and metabolic changes are presented. ...

journal_title：Gastroenterology

authors： Chowdhury AR,Black M,Lorber SH,Chey WY

更新日期：1977-01-01 00:00:00

abstract：:The effect of deoxycholate ingestion, 750 mg per day, on bile acid kinetics, biliary bile acid composition, and biliary lipid secretion was studied in 7 healthy volunteers. Bile acid kinetics were measured by isotope dilution, and hourly outputs of bile acid, cholesterol, and phospholipid were quantitated by a duodena...

journal_title：Gastroenterology

authors： LaRusso NF,Szczepanik PA,Hofmann AF

更新日期：1977-01-01 00:00:00

abstract：:The characteristics are described of an antibody (designated L6) which has virtually absolute specificity for heptadecapeptide gastrin. This antibody binds G17, but does not bind peptide fragments or molecular forms of gastrin comprising G17 with either amino acid deletions, or additions, at the carboxyl- and amino-te...

journal_title：Gastroenterology

authors： Dockray GJ,Taylor IL

更新日期：1976-12-01 00:00:00

abstract：:Three analogues of the carboxyl-terminal tricosapeptide of secretin (S5-27), one with glutamine replacing glutamic acid in position 9 (9-Gln-S5-27), a second with asparagine substituted for aspartic acid in position 15 (15-Asn-S5-27), and a third with both replacements (9-Gln-15-Asn-S5-27) were tested for their abilit...

journal_title：Gastroenterology

authors： Gardner JD,Conlon TP,Fink ML,Bodanszky M

更新日期：1976-12-01 00:00:00

abstract：:In dogs with gastric fistulas, intragastric pressure was measured with a flaccid ballon containing 500 ml of water. Graded doses of dopamine caused graded decreases in intragastric pressure. The effect was blocked by pimozide or by metoclopramide but was not significantly affected by phenoxybenzamine, propranolol, gua...

journal_title：Gastroenterology

authors： Valenzuela JE

更新日期：1976-12-01 00:00:00

abstract：:In order to discover the effect of bile acid synthesis on cholesterol secretion into the bile, 7 rhesus monkeys were studied at various stable interruptions of the enterohepatic circulation of bile acids. In 4 animals, 2.5 and 7.5% interruptions were compared; 2.5 and 15% interruptions were compared in 5 animals. Ther...

journal_title：Gastroenterology

authors： Strasberg SM,Petrunka CN,Ilson RG

更新日期：1976-12-01 00:00:00

abstract：:In recent years the hypothesis that the number of villus cells regulates crypt cell proliferation in the epithelium of the small intestine has been brought forward by a number of investigators. To test this hypothesis, the villus cell population was reduced by clamping the superior mesenteric artery and vein in rats f...

journal_title：Gastroenterology

authors： Rijke RP,Hanson WR,Plaisier HM,Osborne JW

更新日期：1976-11-01 00:00:00

abstract：:Aspirin was given by continuous intravenous infusion to 35 intact cats for 7 days in doses ranging from 25 to 200 mg kg-1 day-1. Gastric mucosal lesions occurred in 50 to 70% of the animals in the various dosage groups, including deep ulcers in 20%. All of the ulcers were in antral mucosa near its border with oxyntic ...

journal_title：Gastroenterology

authors： Bugat R,Thompson MR,Aures D,Grossman MI

更新日期：1976-11-01 00:00:00

abstract：:A prospective screening program was undertaken at the Royal Free Hospital, London, to ascertain the incidence of alpha-1-antitrypsin (AAT) deficiency in patients with liver disease. Quantitative determinations of serum alpha-1-antitrypsin were performed on 469 patients with hepatobiliary disease and 98 subjects with n...

journal_title：Gastroenterology

authors： Fisher RL,Taylor L,Sherlock S

更新日期：1976-10-01 00:00:00

abstract：:Experiments were designed to test the hypothesis that alterations of intestinal motility accompany enteric helminth infections. Motility was measured in rats during the intestinal phase of infection with the nematode Trichinella spiralis by following the transit of radioactive chromium through the gut. Intraduodenal c...

journal_title：Gastroenterology

authors： Castro GA,Badial-Aceves F,Smith JW,Dudrick SJ,Weisbrodt NW

更新日期：1976-10-01 00:00:00

abstract：:A patient is reported with eosinophilic enteritis of the jejunum with fatal evolution. Surgical resection was considered impossible and medical treatment with corticosteroids, elemental diet, parenteral nutrition, and antimicrobials to combat the intestinal bacterial overgrowth failed to control the disease. The destr...

journal_title：Gastroenterology

authors： Tytgat GN,Grijm R,Dekker W,Den Hartog NA

更新日期：1976-09-01 00:00:00

abstract：:Hypercalcemia produced in normal volunteers by intravenous infusions of CaCl2 increased outputs of pancreatic enzyme and gastric acid. Further, hypercalcemia enhanced cholecystokinin (CCK)-stimulated pancreatic enzyme secretion and gallbladder contraction. Our results suggest that hypercalcemia affects pancreatic, gal...

journal_title：Gastroenterology

authors： Malagelada JR,Holtermuller KH,Sizemore GW,Go VL

更新日期：1976-09-01 00:00:00

abstract：:A 36-year-old woman was admitted to hospital with a first attack of acute intermittent porphyria. At the same time increased serum levels of amylase and lipase as well as an increased amylase clearance to creatinine clearance ratio were observed, permitting the diagnosis of acute pancreatitis. The etiology of the latt...

journal_title：Gastroenterology

authors： Kobza K,Gyr K,Neuhaus K,Gudat F

更新日期：1976-09-01 00:00:00

abstract：:The purpose of this study is to determine whether lower esophageal sphincter (LES) incompetency is a common occurrence in patients with liver cirrhosis and contributes to the development of variceal bleeding. Resting LES pressure (17.8 +/- 1.1 mm Hg) in 35 patients with cirrhosis was similar to that of our control pop...

journal_title：Gastroenterology

authors： Eckardt VF,Grace ND,Kantrowitz PA

更新日期：1976-08-01 00:00:00

abstract：:Elevated levels of serum albumin have been noted in patients on chronic methadone maintenance and in heroin addicts. This observation was investigated in rabbits maintained on daily methadone 4 mg per kg of body weight after a period of 3 months on increasing dosage to assure drug tolerance. Albumin distribution and m...

journal_title：Gastroenterology

authors： Rothschild MA,Kreek MJ,Oratz M,Schreiber SS,Mongelli JG

更新日期：1976-08-01 00:00:00

abstract：:This study was undertaken to try to solve the controversy about the influence of gastrointestinal contents on the genesis of bowel sounds, and to probe the respective importance of the various abdominal viscera. Eleven healthy volunteers were intubated by mouth with a multiple-lumen tube. Bowel sounds were recorded fo...

journal_title：Gastroenterology

authors： Politzer JP,Devroede G,Vasseur C,Gerard J,Thibault R

更新日期：1976-08-01 00:00:00

abstract：:Gastric ulcers have been thought to occur only in the pyloric gland area. However, endoscopic examinations using the Congo red test showed that 18 of the ulcers examined (7.8%) were surrounded by an acid-secreting area, and so were in the fundic gland area. Histological examination of specimens obtained by gastrectomy...

journal_title：Gastroenterology

authors： Tatsuta M,Okuda S

更新日期：1976-07-01 00:00:00

abstract：:An animal model for giardiasis was developed using Giardia muris in Swiss albino mice. Intraesophageal inoculation of G. muris cysts caused a reproducible pattern of infection, with trophozoite and cyst counts reaching a maximum on days 5 to 14 after cyst inoculation and thereafter showing a progressive decline. Spont...

journal_title：Gastroenterology

authors： Roberts-Thomson IC,Stevens DP,Mahmoud AA,Warren KS

更新日期：1976-07-01 00:00:00

abstract：:Bile acids cause diarrhea by inducing colonic secretion, probably mediated through the cyclic AMP system. The aim was to determine the effects of an adenylate cyclase inhibitor, propranolol, on deoxycholic acid (DCA) stimulation of net secretion and the cyclic AMP system in the colon. In each of 30 New Zealand white r...

journal_title：Gastroenterology

authors： Conley D,Coyne M,Chung A,Bonorris G,Schoenfield L

更新日期：1976-07-01 00:00:00

abstract：:To clarify the role of fat maldigestion in the pathogenesis of steatorrhea in patients with ileal resection the total and aqueous phase concentrations of bile acid and fatty acid were characterized in 8 such patients (5 patients with small ileal resection, bile acid diarrhea, and steatorrhea less than 20 g per day; 3 ...

journal_title：Gastroenterology

authors： Poley JR,Hofmann AF

更新日期：1976-07-01 00:00:00

abstract：:A patient with recurrent gastrointestinal bleeding caused by hereditary hemorrhagic telangiectasia localized to the small intestine is described. The diagnosis was made by combining two recognized investigational tools-fiberoptic endoscopy and laparotomy. ...

journal_title：Gastroenterology

authors： Greenberg GR,Phillips MJ,Tovee EB,Jeejeebhoy KN

更新日期：1976-07-01 00:00:00

abstract：:Radioactive lithocholate was administered intravenously to female rhesus monkeys with an exteriorized enterohepatic circulation, and the chemical form of biliary radioactivity was defined by thin layer chromatography. Most radioactivity was excreted in bile in the form of unsulfated conjugates (77%), indicating impair...

journal_title：Gastroenterology

authors： Gadacz TR,Allan RN,Mack E,Hofmann AF

更新日期：1976-06-01 00:00:00

abstract：:Twenty cirrhotic patients with esophageal varices and an episode of gastrointestinal bleeding within the previous week underwent hemodynamic studies which used an indicator dilution technique based on selective catheterization of the splanchnic arteries and hepatic vein. Portasystemic shunting of splenic arterial flow...

journal_title：Gastroenterology

authors： Lebrec D,Kotelanski B,Cohn JN

更新日期：1976-06-01 00:00:00

abstract：:Serum group I pepsinogen (PG I) levels have been determined before and at intervals after the administration of betazole hydrochloride (Histalog) in 50 symptomatic postoperative patients, 20 with and 30 without recurrent ulcer, after either a vagotomy and gastric resection or a drainage procedure. In patients with rec...

journal_title：Gastroenterology

authors： Samloff IM,Secrist DM,Passaro E Jr

更新日期：1976-06-01 00:00:00

abstract：:Assessment of the influence of nutritional substrates on the disposition of ingested ethanol from the blood requires, first, an understanding of the influence that these may exert upon ethanol absorption from the gastrointestinal tract. In this report, the effects of various carbohydrates on the intestinal absorption ...

journal_title：Gastroenterology

authors： Broitman SA,Gottlieb LS,Vitale JJ

更新日期：1976-06-01 00:00:00

abstract：:Fifteen (2.2%) of 693 patients with cystic fibrosis seen over an 18-year period developed clinical hepatic disease. In 13 patients all symptoms were secondary to portal hypertension. Ten had hypersplenism and 6 had variceal bleeding, including 3 who developed both conditions. All 5 patients who survived the initial ep...

journal_title：Gastroenterology

authors： Stern RC,Stevens DP,Boat TF,Doershuk CF,Izant RJ Jr,Matthews LW

更新日期：1976-05-01 00:00:00

abstract：:To determine the effect of intraduodenal calcium on pancreatic, gallbladder, and gastric functions in healthy man, a validated perfusion method was employed to quantify total pancreatic, biliary, and gastric outputs during duodenal perfusion of either 6 mM, 12 mM,or 25 mM of elemental calcium (as isotonic calcium chlo...

journal_title：Gastroenterology

authors： Holtermuller KH,Mallagelada JR,McCall JT,Go VL

更新日期：1976-05-01 00:00:00

abstract：:The occurrence of inflammatory bowel disease in all three members of one family is described. Studies of white blood cell chromosomes, histocompatibility antigens, and cellular and humoral immunity failed to explain this unusual phenomenon. However, the appearance of inflammatory bowel disease in an entire family reem...

journal_title：Gastroenterology

authors： Rosenberg JL,Kraft SC,Kirsner JB

更新日期：1976-05-01 00:00:00

abstract：:In some patients with hiatus hernia, vomiting may propel a plug of redundant gastric mucosa into the distal esophagus, where it becomes incarcerated and engorged. Significant bleeding may result. Reduction of the hernia controls the hemorrhage. Endoscopy after the acute episode may demonstrate a gastric mucosal lesion...

journal_title：Gastroenterology

authors： Laforet EG

更新日期：1976-04-01 00:00:00

abstract：:Disordered gustatory acuity was demonstrated in 22 patients with acute viral hepatitis and in 16 patients with chronic liver disease utilizing subjective responses and objective measurements of detection and recognition thresholds and scaling for NaCl, sucrose, HCl, and urea. In patients with early hepatitis and those...

journal_title：Gastroenterology

authors： Smith FR,Henkin RI,Dell RB

更新日期：1976-04-01 00:00:00

abstract：:In seven healthy volunteers pure pancreatic juice was obtained by endoscopic cannulation of the papilla of Vater. Synthetic secretin was intravenously infused in doses doubled every 20 min. The volume of pancreatic juice was proportional to the log of the secretin dose. A significant rise (P less than 0.05) in pancrea...

journal_title：Gastroenterology

authors： Domschke S,Domschke W,Rösch W,Konturek SJ,Wünsch E,Demling L

更新日期：1976-04-01 00:00:00

abstract：:Spontaneous bacterial peritonitis in decompensated cirrhotic patients develops when bacteria invade preexising ascites. It is probable that other transudates such as pleural effusions can be afected in a similar manner. This paper describes a cirrhotic patient with long-standing pleural effusion in whom Escherichia co...

journal_title：Gastroenterology

authors： Flaum MA

更新日期：1976-03-01 00:00:00

abstract：:A patient with post-traumatic seizure disorder developed lymphadenopathy, exfoliative dermatitis, and hepatic failure while on diphenylhydantoin therapy and died in hepatic coma. Autopsy disclosed massive hepatic necrosis. The clinical and pathological pictures are similar to the six previously reported cases of diphe...

journal_title：Gastroenterology

authors： Lee TJ,Carney CN,Lapis JL,Higgins T,Fallon HJ

更新日期：1976-03-01 00:00:00

abstract：:Jejunal absorption of acetate, propionate, and butyrate--the three predominant short chain fatty acids (SCFA's) in small and large intestinal contents--was studied in 5 volunteer subjects. A triple-lumen perfusion technique was employed; the test solutions were isotonic and contained 0, 5, 10, 25, 40, or 50 mM of a SC...

journal_title：Gastroenterology

authors： Schmitt MG Jr,Soergel KH,Wood CM

更新日期：1976-02-01 00:00:00

abstract：:A method of measuring gastric secretions and emptying rates after ingestion of an ordinary (solid-liquid) meal has been developed and validated. The technique quantifies movements of volume across the pylorus using constant duodenal perfusion with a nonabsorbable marker, polyethylene glycol (PEG), which, in turn, quan...

journal_title：Gastroenterology

authors： Malagelada JR,Longstreth GF,Summerskill WH,Go VL

更新日期：1976-02-01 00:00:00

abstract：:The management of colon polyps has been completely revolutionized since the introduction of colonoscopic polypectomy. The reductions in patient time, cost, morbidity, and mortality are major advantages. Reported complications include primarily hemorrhage (1.7%) and frank clinical perforation (0.32%). This report descr...

journal_title：Gastroenterology

authors： Overholt BF,Hargrove RL,Farris RK,Wilson BM

更新日期：1976-01-01 00:00:00

abstract：:The long term administration of chenodeoxycholic acid in man has to be regarded with caution because chenodeoxycholic acid has caused liver damage in various species of animals, including primates. To study the effect of three doses of chenodeoxycholic acid (10, 40, and 100 mg per kg per day) on hepatic function and m...

journal_title：Gastroenterology

authors： Dyrszka H,Salen G,Zaki FG,Chen T,Mosbach EH

更新日期：1976-01-01 00:00:00

abstract：:Frequent occurrence of post-transfusion hepatitis continues despite screening for Australia antigen in blood before transfusion and elimination of commercial donor sources. The majority of these cases appears unrelated to hepatitis B virus. Preoperative, acute, and convalescent serra were screened for evidence of hepa...

journal_title：Gastroenterology

authors： Knodell RG,Conrad ME,Dienstag JL,Bell CJ

更新日期：1975-12-01 00:00:00

abstract：:Serum group I pepsinogen (PG I) levels, basal acid output, and peak acid output (PAO) have been determined in 120 patients, 54 with duodenal ulcer, 14 with prepyloric ulcer, 12 with gastric ulcer, and 40 without ulcer. The correlation between serum PG I and PAO was statistically significant (r = 0.736, P less than 0.0...

journal_title：Gastroenterology

authors： Samloff IM,Secrist DM,Passaro E Jr

更新日期：1975-12-01 00:00:00

abstract：:Fetal bile salt metabolism was assessed by the intravenous infusion of e114C]cholate into 6 monkey fetuses. The placental transfer, fetal plasma clearance, and fetal hepatic excretion of the administered radiolabeled bile salt were measured. Placental transfer averaged 30% of the injected dose, while biliary excretion...

journal_title：Gastroenterology

authors： Little JM,Smallwood RA,Lester R,Piasecki GJ,Jackson BT

更新日期：1975-12-01 00:00:00